Koeppel 2011, p53 and p73 isoforms in Saos-2 osteosarcoma cell line

ChIP-seq against p53 and p73 isoforms (TAp73α and TAp73β) in human osteosarcoma cell lines Saos-2. Saos-2 input DNA sample used as control.

• Raw data was downloaded from GEO series: GSE15780
• Input file format: BED

From H. sapiens (March 2006 NCBI36/hg18).

ChIP-seq data:

	Filename	Description	Feature	GEO-ID
1	GSM501686_ChIP_input.sga	Osteosarcoma input	input	GSM501686
2	GSM501687_ChIP_TAp73alpha_R1.sga	Osteosarcoma TAp73alpha rep1	TAp73alpha	GSM501687
3	GSM501688_ChIP_TAp73alpha_R2.sga	Osteosarcoma TAp73alpha rep2	TAp73alpha	GSM501688
4	GSM501689_ChIP_TAp73beta_R1.sga	Osteosarcoma TAp73beta rep1	TAp73beta	GSM501689
5	GSM501690_ChIP_TAp73beta_R2.sga	Osteosarcoma TAp73beta rep2	TAp73beta	GSM501690
6	GSM501691_ChIP_p53_R1.sga	Osteosarcoma p53 rep1	p53	GSM501691
7	GSM501692_ChIP_p53_R2.sga	Osteosarcoma p53 rep2	p53	GSM501692

Two biological replicates were sequenced for all ChIP samples.

SGA conversion was carried out using bed2sga.pl (ChIP-seq).

• Koeppel M, van Heeringen SJ, Kramer D, Smeenk L, Janssen-Megens E, Hartmann M, Stunnenberg HG, Lohrum M
  Crosstalk between c-Jun and TAp73alpha/beta contributes to the apoptosis-survival balance. Nucleic Acids Res. 2011 Aug;39(14):6069-85. doi: 10.1093/nar/gkr028. Epub 2011 Mar 31. 21459846
• GEO series GSE15780: Interplay between c-Jun and TAp73α/β contributes to the apoptosis-survival balanceInterplay between c-Jun and TAp73α/β contributes to the apoptosis-survival balance