Tao 2011, H3K4me3 in Lsh WT and Lsh-/- MEFs, GSE29393
High-resolution cytosine methylation map of the murine genome modulated by Lsh, a chromatin remodeling family member that has previously been shown to regulate CpG methylation at repetitive sequences. Lsh also controls genome-wide cytosine methylation at nonrepeat sequences and relate those changes to alterations in H4K4me3 modification and gene expression.
Data downloaded from GEO series:
Input file format: SRA
From M. musculus (July 2007 NCBI37/mm9).
The SGA files were gerenerated from GEO accessory text files
provided in Eland export format.
Mapped sequence reads with alignment scores lower than 10 were discared.
The source genome coordidnates were remapped from mouse genome
assembly Feb. 2006 (NCBI36/mm8) to July 2007 (NCBI37/mm9) using
the liftOver software from UCSC.
- Tao Y, Xi S, Shan J, Maunakea A, Che A et al.
Lsh, chromatin remodeling family member, modulates genome-wide
cytosine methylation patterns at nonrepeat sequences.
Proc Natl Acad Sci U S A 2011 Apr 5;108(14):5626-31. PMID:
- GEO series
H3K4me3 modification analysis comparing Lsh WT and Lsh-/- MEFs.