Ultraconserved Gene Regulatory Blocks

Below is a summary of the number of UCNEs found in different species forming a corresponding genomic regulatory block.

Cluster name	Human	Mouse	Opossum	Platypus	Chicken	Zebra_finch	Lizard	Painted_turtle	Xenopus	Fugu	Medaka	Stickleback	Tetraodon	Zebrafish
ZEB2_cluster	134	133	134	132	134	133	130	126	116	67	47	40	56	45
EBF3_cluster	96	96	89	94	96	95	96	88	91	48	48	47	48	62
TSHZ3_cluster	96	96	96	96	96	95	96	89	90	52	46	57	38	63
BCL11A_cluster	92	92	90	92	92	92	88	87	62	26	31	30	23	50
FOXP2_cluster	83	83	83	83	83	83	83	65	78	58	42	59	54	67
ZFHX4_cluster	79	79	79	62	79	77	79	66	78	36	35	37	30	58
DACH1_cluster	73	73	71	73	73	73	72	62	54	36	33	30	35	35
ESRRG_cluster	72	72	72	72	72	72	72	67	65	18	19	24	10	50
NPAS3_cluster	71	71	71	71	71	71	70	69	29	9	9	1	6	39
MEIS2_cluster	67	67	67	52	67	67	67	60	52	51	48	51	42	28
NR2F1_cluster	67	67	66	67	67	67	66	61	51	36	34	39	32	40
ZNF503_cluster	60	60	58	60	60	60	60	57	37	45	43	46	42	44
IRXB_cluster	60	60	60	59	60	60	60	55	48	37	37	41	30	35
TSHZ1_cluster	59	59	59	55	59	59	59	55	9	30	27	28	29	28
NR2F2_cluster	57	57	56	56	57	56	55	53	54	26	24	27	24	35
FOXP1_cluster	49	49	49	49	49	48	47	45	44	30	23	28	30	30
MEIS1_cluster	45	45	45	45	45	45	44	45	41	22	14	0	21	25
POU3F3_cluster	44	44	44	44	44	43	42	42	37	9	18	4	3	24
FIGN_cluster	44	44	44	44	44	42	44	39	36	24	23	26	24	19
BNC2_cluster	43	43	43	43	43	43	42	42	38	24	26	25	24	17
POU3F2_cluster	42	42	42	40	42	42	42	39	34	9	8	9	8	9
PBX3_cluster	42	42	42	42	42	41	40	40	34	32	34	35	30	31
RUNX1T1_cluster	41	41	41	41	41	41	41	38	34	13	11	12	9	17
TLE4_cluster	41	40	41	39	41	41	41	39	39	1	0	0	0	0
LMO4_cluster	40	40	40	40	40	40	40	38	36	17	15	18	14	22
ZNF521_cluster	40	40	40	37	40	40	39	35	6	20	19	18	14	6
NR4A2_cluster	37	37	37	37	37	35	37	33	36	29	28	30	28	21
SATB1_cluster	37	37	37	37	37	37	37	33	34	14	12	17	15	14
OTP_cluster	35	35	34	34	35	35	35	32	33	22	21	20	22	24
TFAP2A_cluster	34	34	34	34	34	34	33	33	32	19	22	20	16	20
AUTS2_cluster	34	34	33	13	34	34	31	33	32	13	17	19	13	16
PAX6_cluster	33	33	33	33	33	33	33	33	30	6	8	10	9	22
SALL3_cluster	33	33	33	29	33	33	33	30	31	19	26	24	19	18
ZFPM2_cluster	33	33	33	33	33	33	33	31	29	28	28	27	28	28
PAX9_cluster	32	32	32	32	32	32	32	24	22	11	7	11	7	15
PROX1_cluster	31	31	31	31	31	31	31	28	30	6	8	5	3	18
ZFHX3_cluster	31	31	31	31	31	31	22	29	24	6	5	6	6	10
IRXA_cluster	31	31	31	31	31	31	31	30	30	25	24	25	20	22
LMO3_cluster	30	30	30	26	30	30	30	26	11	0	8	15	0	19
HOXD_cluster	30	30	30	30	30	30	29	29	29	23	21	23	22	19
SOX2_cluster	29	28	29	29	29	29	29	28	27	9	9	11	11	17
SP3_cluster	28	28	28	28	28	28	28	26	28	18	18	18	16	13
BHLHE22_cluster	28	28	28	28	28	28	28	25	26	12	14	13	13	14
SOX6_cluster	27	27	27	27	27	27	27	26	15	13	15	15	13	19
ZIC1_cluster	27	27	27	26	27	27	27	26	22	13	14	13	11	13
EBF1_cluster	27	27	27	27	27	27	27	26	19	2	2	3	4	11
BARHL2_cluster	26	26	24	26	26	26	26	23	25	17	18	17	11	19
SOX5_cluster	26	26	26	26	26	26	25	24	15	6	7	6	7	10
FOXD3_cluster	25	25	24	25	25	22	25	25	23	18	17	16	17	16
POU4F1_cluster	25	25	25	25	25	25	25	22	25	9	8	11	8	11
VTI1A_cluster	24	24	24	24	24	24	24	21	20	18	15	11	16	18
HOXA_cluster	24	24	24	24	24	24	24	24	24	3	3	5	3	6
SIX2_cluster	22	22	22	19	22	22	22	22	21	5	7	7	5	13
PITX2_cluster	22	22	22	22	22	22	22	21	21	9	9	12	8	11
PTBP2_cluster	21	21	21	21	21	21	21	20	17	1	1	3	1	6
VRK1_cluster	21	21	21	20	21	21	21	21	20	7	9	12	6	14
SMAD3_cluster	21	21	21	21	21	19	21	21	19	12	11	12	11	9
EMX2_cluster	20	20	20	20	20	20	20	16	14	16	15	18	11	17
WWOX_cluster	20	20	20	20	20	20	19	19	19	12	10	10	12	10
KLHL14_cluster	20	20	20	20	20	20	20	16	20	10	9	10	7	9
SP8_cluster	20	20	20	20	20	20	20	20	19	11	10	11	11	11
CASZ1_cluster	19	19	16	19	19	19	8	17	16	13	11	12	12	11
NFIA_cluster	19	19	18	17	19	19	18	18	18	0	2	7	2	6
FOXG1_cluster	19	19	19	19	19	19	19	18	11	0	1	0	0	9
SHOX2_cluster	19	19	19	19	19	18	19	17	19	16	16	14	15	13
MECOM_cluster	19	19	19	19	19	19	19	19	18	8	13	13	4	10
NKX6-1_cluster	19	19	18	16	19	19	18	19	19	15	7	2	14	17
ZNF238_cluster	18	18	18	18	18	18	18	16	15	5	4	4	3	11
OTX2_cluster	18	18	17	18	18	18	18	17	17	7	5	6	7	5
TSHZ2_cluster	18	18	18	18	18	18	18	17	18	11	10	11	10	8
POU4F2_cluster	18	18	18	18	18	18	18	17	16	13	9	13	11	15
LHX1_cluster	17	17	17	17	17	17	17	14	14	8	8	8	9	11
GBX2_cluster	17	17	9	17	17	17	17	16	13	7	6	1	6	8
MAB21L2_cluster	17	17	17	17	17	17	17	16	15	9	8	9	9	9
POU6F2_cluster	17	15	17	17	17	17	16	17	17	11	10	11	9	9
TOX_cluster	17	17	17	17	17	17	17	16	15	0	0	0	0	5
TCF4_cluster	16	16	16	16	16	6	16	12	15	1	1	3	0	3
OTX1_cluster	16	16	16	16	16	16	16	14	16	5	8	4	5	9
PRDM8_cluster	16	16	16	14	16	16	16	14	16	14	12	3	12	13
ODZ3_cluster	16	16	16	14	16	16	16	15	15	3	4	3	3	5
ARX_cluster	16	16	16	14	16	16	16	14	16	6	4	5	5	8
PAX2_cluster	15	15	12	13	15	15	15	13	15	14	12	13	14	13
BCL11B_cluster	15	15	15	15	15	15	13	13	14	4	7	7	3	7
DACH2_cluster	15	15	14	14	15	15	15	15	15	0	0	0	0	10
HMX2_cluster	14	14	14	14	14	14	14	14	13	11	10	11	10	10
FOXB1_cluster	14	14	14	14	14	14	11	14	11	7	5	6	6	6
TFAP2B_cluster	14	14	14	14	14	14	14	14	13	4	5	6	5	8
ISL1_cluster	13	13	13	13	13	13	13	13	13	5	3	8	1	10
LHX9_cluster	12	12	12	11	12	12	12	12	8	7	7	7	4	10
LBX1_cluster	12	12	12	12	12	12	12	12	12	3	3	2	3	3
MAB21L1_cluster	12	12	12	12	12	12	12	12	11	8	9	9	8	6
ZIC2_cluster	12	12	12	12	12	12	12	12	12	8	7	8	8	9
SATB2_cluster	12	12	12	10	12	12	12	11	10	1	1	0	0	1
TLX3_cluster	12	12	12	10	12	12	12	8	7	0	0	0	0	0
ID4_cluster	12	12	12	11	12	12	11	12	11	3	3	3	3	3
ETV1_cluster	11	11	11	11	11	11	11	10	11	5	5	6	4	5
ST18_cluster	11	11	11	11	11	11	11	11	11	8	6	8	8	8
TBX2_cluster	10	10	10	10	10	10	10	9	10	4	6	7	7	9
ZNF608_cluster	10	10	8	10	10	10	10	9	7	0	0	0	0	0
NFIB_cluster	10	10	10	10	10	10	10	10	10	3	4	4	2	1
PAX5_cluster	10	10	10	10	10	10	10	10	9	1	0	0	0	0
POU3F4_cluster	10	10	10	8	10	10	10	9	9	2	1	3	2	0
KIF14_cluster	9	9	9	9	9	9	9	9	6	4	4	3	5	8
CADM1_cluster	9	9	9	7	9	9	8	9	2	0	1	0	0	2
SOX21_cluster	9	9	9	9	9	9	9	7	8	7	8	8	8	5
LRPPRC_cluster	9	9	9	8	9	9	9	8	9	2	2	1	2	4
SOX14_cluster	9	9	9	9	9	9	8	8	9	7	7	6	6	7
PRDM13_cluster	9	9	9	9	9	9	9	9	9	2	2	2	2	4
TNFAIP3_cluster	9	9	9	9	9	9	9	9	8	6	7	7	3	6
LHX2_cluster	9	9	9	9	9	9	9	9	9	5	5	6	4	4
DRGX_cluster	8	8	8	8	8	8	8	8	6	7	5	7	6	7
GSX1_cluster	8	8	8	8	8	8	8	8	8	4	4	4	4	4
ONECUT1_cluster	8	8	8	7	8	8	0	8	8	1	1	1	1	5
TMEM114_cluster	8	8	8	8	8	8	7	7	6	2	0	0	1	4
DLX1_cluster	8	8	8	8	8	8	8	8	7	7	7	7	7	6
DHX15_cluster	8	8	8	8	8	8	8	8	5	3	3	3	1	2
SYNCRIP_cluster	8	8	8	8	8	8	8	8	7	1	3	3	1	4
LACE1_cluster	8	8	8	8	8	8	8	8	8	3	3	2	3	2
MICALL2_cluster	8	8	7	7	8	8	3	8	8	6	5	5	6	7
VPS13B_cluster	8	8	8	8	8	8	8	8	7	3	2	3	3	0
ZNF703_cluster	8	8	7	8	8	7	8	8	8	6	6	6	5	5
DDX3X_cluster	8	8	8	8	8	8	8	8	8	4	3	5	1	3
RNF220_cluster	7	7	6	7	7	7	7	6	7	5	3	4	4	7
ELTD1_cluster	7	7	7	7	7	7	7	7	6	2	2	3	2	1
PBX1_cluster	7	7	7	5	7	7	7	6	5	2	5	5	2	4
RNF144A_cluster	7	7	7	7	7	7	7	7	6	3	3	3	3	3
MIR4796_cluster	7	7	7	5	7	7	7	7	7	0	0	0	0	0
PHOX2B_cluster	7	7	7	7	7	7	5	7	7	5	5	5	5	5
MEF2C_cluster	7	7	7	7	7	6	7	7	7	3	3	3	2	3
FAF1_cluster	6	6	6	6	6	6	6	5	6	2	1	3	1	2
GATA3_cluster	6	6	6	6	6	6	5	6	6	6	4	3	6	6
CELF2_cluster	6	6	6	6	6	6	5	6	6	3	3	3	3	4
MIR4307_cluster	6	6	6	6	6	6	6	6	4	0	0	0	0	0
ESRRB_cluster	6	6	6	6	6	6	6	6	2	5	4	4	4	5
MIR4318_cluster	6	6	6	6	6	6	6	5	5	0	0	0	0	0
SMAD2_cluster	6	6	5	6	6	6	6	5	6	0	2	2	1	5
TANK_cluster	6	6	6	6	6	6	6	6	6	3	3	3	3	3
PAX1_cluster	6	6	6	6	6	6	6	6	6	5	4	4	5	5
FBXO8_cluster	6	6	6	6	6	6	6	6	6	0	0	0	0	2
PPIC_cluster	6	6	6	6	6	6	6	5	6	2	2	1	2	2
NEUROD6_cluster	6	6	6	6	6	6	6	6	6	3	2	3	1	4
GLI3_cluster	6	6	6	6	6	6	6	6	6	5	2	5	4	5
AK5_cluster	5	5	5	5	5	5	5	5	5	3	2	3	3	1
ZBTB16_cluster	5	5	5	3	5	5	5	5	4	4	4	4	2	4
GXYLT1_cluster	5	5	0	5	5	5	4	5	5	1	1	1	1	0
POLR3B_cluster	5	5	5	5	5	5	5	5	5	3	3	3	3	3
MSI2_cluster	5	5	5	5	5	5	4	4	4	3	3	2	3	4
EN1_cluster	5	5	5	1	5	5	5	5	0	3	2	3	3	3
SP5_cluster	5	5	5	5	5	5	5	5	5	5	5	5	5	5
OLIG2_cluster	5	5	5	5	5	4	5	5	5	0	1	1	0	1
ZSWIM6_cluster	5	5	5	4	5	5	5	5	5	1	1	2	1	0
TNPO1_cluster	5	5	5	4	5	5	5	5	5	2	1	2	1	4
TFAP2B_cluster	5	5	5	5	5	5	5	5	5	1	2	1	2	0
HDAC9_cluster	5	5	5	5	5	5	5	5	5	3	3	3	3	2
CHD7_cluster	5	5	5	5	5	5	5	5	5	1	1	1	1	4
EYA1_cluster	5	5	5	5	5	5	5	5	5	4	3	4	3	4
TRPS1_cluster	5	5	5	5	5	5	5	5	5	0	0	0	0	3
ZC3H3_cluster	5	5	5	4	5	5	5	5	4	0	1	2	1	1
EBF2_cluster	5	5	5	3	5	5	5	5	2	2	2	2	2	1
ZIC3_cluster	5	5	5	5	5	4	2	5	5	3	4	4	4	4
DIP2C_cluster	4	4	4	4	4	4	4	4	3	0	0	0	0	0
PTF1A_cluster	4	4	4	4	4	4	4	4	4	3	3	3	3	4
NTM_cluster	4	4	4	4	4	4	4	4	2	0	0	0	0	0
LMO1_cluster	4	4	4	4	4	4	4	4	4	3	2	3	3	3
TEAD1_cluster	4	4	4	4	4	4	4	4	4	3	4	4	2	3
DBX1_cluster	4	4	4	4	4	4	2	2	1	3	1	2	3	4
SOX1_cluster	4	4	4	3	4	4	4	4	4	2	2	2	2	2
G2E3_cluster	4	4	4	4	4	4	4	4	1	1	1	1	1	2
NRXN3_cluster	4	4	4	4	4	4	4	4	3	1	1	1	1	2
ZNF423_cluster	4	4	4	4	4	4	4	4	4	0	1	1	1	1
LUC7L3_cluster	4	4	4	4	4	4	4	4	3	4	3	3	4	4
DPH1_cluster	4	4	3	3	4	4	3	4	2	1	1	1	1	1
CELF4_cluster	4	4	4	4	4	4	4	4	3	0	0	0	0	0
KCTD15_cluster	4	4	4	4	4	4	4	4	4	3	3	3	2	3
AFF3_cluster	4	4	4	4	4	4	4	4	1	0	0	0	0	0
MYT1L_cluster	4	4	4	4	4	4	4	4	4	4	4	4	3	4
MBD5_cluster	4	4	4	4	4	4	4	4	1	1	1	1	0	2
BAZ2B_cluster	4	4	4	4	4	4	4	4	4	3	2	3	2	2
UBE2E3_cluster	4	4	4	4	4	4	4	4	3	0	0	0	0	2
CADPS_cluster	4	4	4	4	4	4	4	4	3	2	3	3	2	3
RARB_cluster	4	4	4	4	4	4	4	4	4	1	0	1	0	0
MBNL1_cluster	4	4	4	4	4	4	4	4	4	3	3	3	3	2
CPEB2_cluster	4	4	4	4	4	4	4	4	4	2	1	1	2	1
GSX2_cluster	4	4	4	4	4	4	4	4	4	4	3	2	2	2
HHIP_cluster	4	4	4	4	4	4	4	4	4	2	3	2	2	3
SAR1B_cluster	4	4	4	4	4	4	4	4	4	0	1	1	1	1
FLJ42709_cluster	4	4	4	4	4	4	4	4	2	3	3	3	1	3
NIPBL_cluster	4	4	4	4	4	4	4	4	2	2	2	2	2	2
ARL15_cluster	4	4	4	4	4	4	4	4	3	2	1	2	2	1
GMDS_cluster	4	4	4	4	4	4	4	4	3	0	1	1	1	0
MARCKS_cluster	4	4	4	4	4	4	4	4	4	3	3	3	3	1
CADPS2_cluster	4	4	4	4	4	4	4	4	4	1	0	1	0	2
CUX1_cluster	4	4	4	4	4	4	3	4	3	0	0	0	0	1
CDK14_cluster	4	4	4	1	4	4	4	4	4	0	0	0	0	0
NCOA2_cluster	4	4	4	3	4	4	4	4	4	2	1	3	1	3
BARHL1_cluster	4	4	4	4	4	4	0	4	4	2	1	0	0	2
ANXA1_cluster	4	4	4	4	4	4	4	4	4	0	0	0	0	1
DCAF12L2_cluster	4	4	4	4	4	4	4	4	4	0	0	0	0	0
SOX3_cluster	4	4	4	4	4	4	4	4	4	2	2	3	3	3
POU3F1_cluster	3	3	3	3	3	3	3	3	3	3	3	1	3	3
MIR205HG_cluster	3	3	3	3	3	3	3	3	2	0	0	0	0	0
SRSF11_cluster	3	3	3	3	3	3	3	3	3	3	3	3	3	3
LPHN2_cluster	3	3	3	3	3	3	3	3	2	0	0	0	0	0
MLLT10_cluster	3	3	3	3	3	3	3	2	3	1	0	1	1	1
ARID5B_cluster	3	3	3	3	3	3	3	3	2	0	0	0	0	1
EGR2_cluster	3	3	3	3	3	3	3	3	3	1	1	1	1	2
ZMIZ1_cluster	3	3	3	3	3	3	3	3	1	1	1	1	1	1
CTBP2_cluster	3	3	2	2	3	3	3	3	0	1	1	1	1	0
NKX6-2_cluster	3	3	1	3	3	3	3	3	3	3	1	2	3	1
DBX2_cluster	3	3	2	3	3	3	3	3	3	1	1	2	1	0
CUX2_cluster	3	3	3	3	3	3	3	3	3	3	3	3	3	1
SLC10A2_cluster	3	3	3	3	3	3	3	3	2	0	0	0	0	0
SOX1_cluster	3	3	3	3	3	3	3	3	3	2	2	2	1	3
LIN52_cluster	3	3	3	3	3	3	3	3	3	2	2	2	2	1
TCF12_cluster	3	3	3	3	3	3	3	3	3	2	2	2	2	3
FLJ45079_cluster	3	3	3	3	3	3	3	3	0	0	0	0	0	0
HOXB_cluster	3	3	3	3	3	2	3	3	3	1	1	1	0	2
KCNS3_cluster	3	3	2	3	3	3	3	3	2	0	0	0	0	0
NRXN1_cluster	3	3	3	3	3	3	3	2	3	0	0	0	0	0
XPO1_cluster	3	3	3	3	3	3	3	2	3	3	3	3	1	2
ERBB4_cluster	3	3	3	3	3	3	3	3	3	0	0	0	0	0
MAFB_cluster	3	3	3	3	3	3	3	3	2	0	1	0	1	1
NRIP1_cluster	3	3	1	3	3	3	3	2	2	0	1	1	0	2
WNT5A_cluster	3	3	3	3	3	3	2	3	1	0	0	0	0	0
FHIT_cluster	3	3	3	3	3	3	3	3	1	0	0	0	0	0
SLIT2_cluster	3	3	3	3	3	3	3	3	3	0	0	0	0	0
HNRNPD_cluster	3	3	3	3	3	3	3	3	3	1	1	2	1	1
ODZ2_cluster	3	3	3	3	3	3	3	3	3	0	0	0	0	1
CPEB4_cluster	3	3	3	3	3	3	3	1	3	3	2	3	3	3
TSG1_cluster	3	3	3	3	3	3	3	3	2	1	1	1	1	0
ARID1B_cluster	3	3	3	3	3	3	3	3	0	1	1	2	1	0
QKI_cluster	3	3	3	3	3	3	3	1	3	0	1	1	1	0
IKZF1_cluster	3	3	3	3	3	3	3	3	3	3	3	3	3	3
DLX6_cluster	3	3	2	2	3	3	2	3	3	2	2	2	2	2
LMBR1_cluster	3	3	3	3	3	3	3	3	3	3	3	3	3	3
DMRT2_cluster	3	3	3	3	3	3	3	3	3	3	3	3	3	3
PTPRD_cluster	3	3	3	3	3	3	3	3	3	2	2	2	2	2
GAS1_cluster	3	3	3	2	3	3	3	3	3	2	2	2	2	2
ONECUT2_cluster	2	2	2	2	2	0	2	2	2	0	0	0	0	0
FOXB2_cluster	2	2	2	2	2	2	2	2	2	2	2	2	2	2

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