Genome-wide tag scanner for nuclease off-sites

Target Databases

Search ZFN Sites
(min 8 nt - max 60 nt)

(min 8 nt - max 60 nt)

     (one or two values separated by a comma)   
(max 2)     

Background: Based on the Tagger software, this application is intended to search genomes for specific target sites and off-target sites, such as for pairs of zinc finger proteins (ZFPs), zinc finger nucleases (ZFNs) and modified homing endonucleases. This can either define a zinc finger nucleases (hetero-dimer) or allow for homo-dimers depending on the status of the checkbox in the input form.

Provisional PDF: BMC Bioinformatics
ZFN-Site searches genomes for zinc finger nuclease target sites and off-target sites
Thomas J Cradick, Giovanna Ambrosini, Christian Iseli, Philipp Bucher, Anton P McCaffrey
BMC Bioinformatics 2011, 12:152 (13 May 2011)

Last update 15 June 2012