EPD's 40th Anniversary Symposium is open for registration !!! (click here)
(taking place in Geneva on Sep 4 2026, just after
ECCB 2026,
for more information, see https://epd.expasy.org/EPD_symposium2026/)
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| 2024-03-18 | Join IBIS! New TF binding specificity challenge open for registration https://ibis.autosome.org [showhide] IBIS is an open challenge in Inferring Binding Specificities of human transcription factors from multiple experiment types with bioinformatics & machine learning. Have a look at our website, participate in our discussion forums, or contact us by email:
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PWMTools is a Web interface for Position Weight Matrix (PWM) model generation and evaluation.
PWMs have become a popular method for representing patterns in biological sequences, and they are used to extensively study protein-DNA binding specificity, in particular for transcription factor binding site (TFBS) identification.
PWMTools includes the following tools:
- PWMTrain which is a Web-based software pipeline used to derive TFBS models from DNA sequences such as HT-SELEX and SMiLE-seq
- PWMEval which is a Web tool to evaluate PWM models based on ChIP-seq data
- PWMScore which is a Web tool to compute the binding occupancy score of a set of genomic sequences, given a PWM model
- PWMScan which is a Web tool to scan entire genomes of common model organisms with a PWM
Last update April 2021
